sildenafil citrate

Sildenafil citrate tablets 100mg were originally created in 1996 by the pharmaceutical company, Pfizer, to treat angina and hypertension, but researchers noticed it was more effective in treating impotence. In 1998, it was approved by the U.S. Food and Drug Administration (FDA), the European Medicines Agency (EMA) and the UK. While many other similar drugs have been developed since, this one has withstood the test of time and is still a preferred treatment for impotence.

What is Impotence?

Impotence, more commonly known as erectile dysfunction (ED), is when a man can't get or keep an erection long enough for sexual activities. It is a highly prevalent condition endured by men across the globe. An analysis of the Massachusetts Male Aging Study found that 322 million people worldwide have some degree of this condition, a 112% increase over the course of 30 years.

Research done by the British Association of Urological Surgeons (BAUS) uncovered that 90% of people with ED also have an underlying physical condition as the likely cause, making it a good early warning sign of vascular issues like heart disease. The tiny blood vessels in the penis are one of the first to be damaged, often years before other, more serious symptoms occur.

Other likely causes include hormonal imbalances, obesity, diabetes, and nerve damage. 10% of ED occurrences stem from psychological barriers like chronic stress or performance anxiety.

While impotence drugs like sildenafil citrate 100mg provide temporary relief, targeting the root cause with sustainable lifestyle changes and diligent annual check-ups will help patients in the long term.

How Can Sildenafil Citrate Help?

The inability to get hard during sexual activities is not uncommon. Whether it only occurs sometimes or every time, it can have a heavy impact on a man's confidence and sense of self-worth. Those who have experience with this condition should be aware that it does not make an individual less masculine; it means that there is either a mental or physical roadblock hindering the process.

This is where sildenafil citrate 100mg comes in to save the day. It helps men maintain a stiff erection during intercourse by boosting genital circulation. When taken orally 30 minutes to an hour before sex, it provides the user with 4 to 6 hours of ED protection, giving couples ample time and flexibility to partake in intimate activities.

How sildenafil citrate works is similar to how other phosphodiesterase type 5 (PDE5) inhibitors function. They increase nitric oxide (NO) and prevent the PDE5 enzyme from degrading cyclic guanosine monophosphate (cGMP), a necessary component for achieving an erection. It signals the vasodilation or widening of genital blood vessels, allowing more blood to flow to the penis, resulting in a sufficiently stiff erection when stimulated sexually.

What Are Generic Treatments?

Some people are completely unaware that sildenafil citrate tablets uses the same chemical found in the popular copyrighted medication Viagra.

Generics like sildenafil citrate are the same as branded drugs and contain identical ingredients. They provide therapeutic effects identical to their name-brand counterpart but are more accessible due to their low cost and online availability.

Pfizer, the company that created sildenafil citrate tablets 100mg, originally held exclusive rights to the active ingredient. At that time, it could only be found in the trademarked medication, Viagra. This exclusivity came to an end in 2012 when their patent expired.

Once a formula's patent has expired, other pharmaceutical companies can begin producing their own treatments using the same substance. These generic manufacturers save money on research, development, and advertising. This gives sellers the ability to pass the savings on to their customers. This system makes sure that no single company has total indefinite control over the sildenafil citrate formula.

How Does Sildenafil Citrate Compare to the Alternatives?

Active Ingredient	Dosage	Formula	Activation Time	How Long it Lasts	Risks
Sildenafil Citrate	100mg, 150mg, 200mg	Hard Pill	30 to 60 minutes	4 to 6 hours	Not suitable for patients with heart problems
Vardenafil	20mg	Hard Pill	30 to 60 minutes	4 to 6 hours	Not suitable for patients with heart problems
Tadalafil	20mg, 40mg, 60mg	Hard Pill	30 to 45 minutes	Up to 36 hours	Not suitable for patients with heart problems

Finding the Right Dosage

Reputable pharmaceutical web stores provide quality generics like sildenafil citrate online to experienced users who already know what their needs are. Those taking this medication for the first time should get professional dosing advice from their doctor before beginning treatment. Health care providers should be able to access any information about existing and recent conditions, as well as drugs being taken, as it could affect the recommended sildenafil citrate dose.

A review of 67 double-blind placebo-controlled trials concluded that 50mg and 100mg of sildenafil citrate were tolerated well by adult-aged men, including the elderly. New users are typically told to start on the lowest available strength. If it doesn't work the first time, doctors often advise patients to try it in separate sessions 8 more times. If success is still not achieved, continue increasing the dose until it works.

Safe Usage

sildenafil citrate has been approved by reputable government regulatory bodies like the FDA and EMA since 1998, meaning it has proven to be a tried and true remedy. Responsible use on the patient's part, however, is still necessary. Users need to learn how to use sildenafil citrate tablets properly and adhere to the instructions provided by the manufacturer or their healthcare provider closely.

For oral administration, swallow the pills whole along with a glass of water, 30 to 60 minutes before intended intercourse. Don't crush, chew or break the pill. Doing so will impact absorption into the body and reduce its effectiveness. In addition, do not exceed one dose within a 24-hour period.

Sildenafil citrate is meant to be taken on demand, meaning it should only be used if sex is imminent. Although this medicine provides temporary relief from erectile dysfunction, it's not an aphrodisiac or male enhancement pill. To get the intended effect, patients will be required to stimulate the penis.

Potential Interactions and Adverse Reactions from Sildenafil Citrate

According to NIH, more than 1 in 100 people will experience negative reactions from taking the drug. Patients can minimise this risk by only using it as instructed. In most cases, however, sildenafil citrate side effects are mild, manageable and temporary.

Common reactions include headache, facial flushing, stuffy nose, dizziness and stomach ache. Users should also keep an eye out for symptoms of low blood pressure because this medication has been reported to lead to these issues. This is an incomplete list. To view all known reactions alongside other necessary details, take a look at the Patient Information Leaflet (PIL) to find out how sildenafil citrate works before commencing treatment.

If the user experiences facial flushing or headaches, patients should get to a cool place and drink plenty of water. They can also try reducing their alcohol and/or caffeine intake and avoiding heavy meals.

Contraindications - Who Should Avoid This Treatment?

Sildenafil citrate tablets are not suitable for everyone. Patients with certain conditions or taking particular medications should avoid this drug or be especially vigilant about addressing them with a doctor before starting.

People using any kind of nitrates for angina should not take PDE5 inhibitors in any capacity, as the combination could result in dangerously low blood pressure levels. Those who have suffered a heart attack or stroke, or have a penile deformity should either avoid or keep their doctor informed about their use of sildenafil citrate.

Only a healthcare professional can properly instruct users on how to use sildenafil citrate tablets. Patients should discuss the matter with their doctor before beginning any treatment.

The Value of Customer Reviews

Thanks to modern innovation, users don't have to take the company's word for it when it comes to how effective drugs like sildenafil citrate are for ED. There is an entire network of users on the internet ready and willing to share their personal experiences with their peers.

Marketing research has come to the conclusion that most customers read and are influenced by reviews from fellow buyers. 55% will not even consider an item or business without a 4-star rating or higher. This motivates our industry to only sell the highest quality sildenafil citrate generics and empowers newer users to make an informed choice when it comes to their selection.

Disclaimer: The information provided here is for education purposes only and not a substitution or replacement for medical advice. Always get personal professional guidance from an expert before starting on sildenafil citrate or any new medication.